Conversely, morphine and -endorphin induced both self-tolerance and cross-tolerance to SM and exenatide [72]
Which HRT delivery methods are affected Affected by GLP-1 medications (oral delivery): Oral estrogen tablets (conjugated equine estrogens, estradiol) Oral progesterone (micronized progesterone, such as Utrogestan) Oral progestins (norethisterone, medroxyprogesterone) Oral testosterone (testosterone undecanoate) NOT affected by GLP-1 medications (non-oral delivery): Transdermal estrogen patches Topical estrogen gels and creams Vaginal estrogen rings or suppositories Progesterone-releasing IUD (Mirena) Transvaginal progesterone Testosterone injections Testosterone pellets Testosterone patches or gels The distinction is simple
AOD-9604 enhances one component of energy balance (fat oxidation from adipose stores) without creating the negative energy balance that results from appetite suppression or the metabolic rate increases seen with thermogenic compounds
References Liang Z, Wang N, Shang L, et al
Nausea and vomiting, common side effects of GLP-1 therapy, can lead to volume depletion, further straining kidney function when paired with medications that inhibit the renin-angiotensin system (RAAS)
